Predictive value of blood eosinophil count in COPD

Blood eosinophil count to predict bronchial eosinophilic inflammation in COPD.

Chronic obstructive pulmonary disease (COPD) is an inflammatory disease of the airways. There is evidence that maintenance treatment with inhaled corticosteroids (ICS) in COPD results in a reduction in the mean rate of exacerbations, and improvement in quality of life and lung function [1]. However, ICS therapy has been associated with increased risk of oropharyngeal candidiasis, hoarseness and...

Clinical implications of blood eosinophil count in patients with non-asthma–COPD overlap syndrome COPD

BACKGROUND Recent studies that assessed the relevance of the blood eosinophil count as a biomarker in patients with COPD may have overestimated it because they included patients with asthma-COPD overlap syndrome (ACOS). We investigated the clinical implications of the blood eosinophil count in patients with non-ACOS COPD. PATIENTS AND METHODS From a Korean COPD Subtype Study (KOCOSS) cohort, ...

Effect of inhaled corticosteroids on blood eosinophil count in steroid-naïve patients with COPD

INTRODUCTION Sputum and blood eosinophil counts have attracted attention as potential biomarkers in chronic obstructive pulmonary disease (COPD). One question regarding the use of blood eosinophils as a biomarker in COPD is whether their levels are affected by the use of inhaled corticosteroids (ICS), which are commonly prescribed for COPD. METHODS We performed a retrospective analysis of per...

The Prognostic Value of White Blood Cells Count in Patients with Myocardial Infarction

Background: Ischemic heart disease and acute myocardial infarction is one of the most dramatic manifestations in one of the most investigated fields in the past few decades. In this study, the prognostic value of white blood cells count in patients with myocardial infarction (MI) was investigated in a six months follow-up. Methods: In this cohort study, 106 patients with MI were investigated. ...

Mental stress and eosinophil count.